Individuals with type 2 diabetes (T2D) commonly exhibit alterations in circulating lipoprotein particles and their subfractions, captured as increased levels of triglyceride-rich apolipoprotein B (apoB)-containing lipoproteins, e.g. very large very low-density lipoproteins (VLDL) and small low-density lipoproteins (LDL), and decreased levels of high-density lipoproteins (HDL) [1–10]. Here, APOB is linked to type 2 diabetes mellitus.