In this model, clinical symptoms such as chest pain, respiratory distress, level of consciousness, and anorexia, biomarkers such as CRP, WBC, NLR, AST, BUN, and ALT, underlying diseases, chronic nervous disorders and HTN, as well as variables such as age, hospitalization in ICU, and discharge status a statistically significant correlation with LOHS. This evidence concerns the gene GPT and hypertensive disorder.