Various biochemical indicators are important in detecting liver impairment and renal dysfunction of which ALT and AST are common liver enzymes that may be used to detect changes in liver function69, and screening tests for renal functioning are urea and creatinine70, and serum total protein analysis provides an estimate of nutritional status as well as a diagnostic assessment for changes in renal functioning71. This evidence concerns the gene GPT and Abnormal renal physiology.