Hepatocyte-specific, Cre-mediated excision of the floxed STOP cassette allows expression of the CAG promoter-driven human Myc, leading to a typical phenotype with hepatomegaly and paraneoplastic alopecia in double transgenic Alb-Cre;CAG-Myc mice (ABC-Myc, Figs. 1b and S1a). Here, ALB is linked to alopecia.