While the poorly differentiated histology is consistent with the pediatric C2 phenotype, some tumor areas also contain histologic features of the subclassification of pediatric hepatoblastomas with hepatocellular carcinoma features that were previously called transitional liver cell tumors (TLCT)9 (Fig. 1g), indicating that some ABC-Myc tumor cells have features of HCN-NOS (Hepatocellular Malignant Neoplasm, Not Otherwise Specified) that frequently presents phenotypic plasticity. The gene discussed is MYC; the disease is hepatocellular carcinoma.