The TCGA database and IHC staining showed that PHLDA2 expression was upregulated in HCC tissues, and the PHLDA2 mRNA level in HCC samples was correlated with HCC patients’ prognosis and the DAGLA level (Fig. 5B, C, Supplementary Fig. S5A–C). Here, PHLDA2 is linked to hepatocellular carcinoma.