Notably, unlike WT mice, Bcl3−/− mice did not have a significantly increased subchondral osteosclerosis in the bone loading regions of the tibial plateau of DMM‐induced knees compared to contralateral controls, indicative of reduced disease (Figure 6E and Supplementary Figure 7, available at http://onlinelibrary.wiley.com/doi/10.1002/art.42639). The gene discussed is BCL3; the disease is osteosclerosis.