IL1B and infection: Indeed, the induction of mitophagy protects against accumulation of mitochondrial damages such as mtDNA release (in the case of P. aeruginosa), or mtROS-derived oxidative stress (as reported for L. monocytogenes, Y. pestis, and V. splendidus), which could lead to the activation of the inflammasome, the maturation of pro-inflammatory IL-1β and IL-18 cytokines, and subsequent elimination of the infection [102].