Similarly, previous studies have revealed that α7nAChR agonists could regulate the proliferation and differentiation of osteoblasts (35) and periodontal ligament cells (33, 37) by regulating the WNT/β-catenin signaling pathway or exerts its neuroprotective function in Parkinson’s disease model via WNT/β-catenin signaling (38). Here, CHRNA7 is linked to Parkinson disease.