CD63 and retinoblastoma: In AH from treated RB eyes, the sEV subpopulation distribution appeared more homogenous, with a significantly higher subpopulation of mono-CD63+ sEVs (Tx AH, 43.5 ± 14.7% vs. DX AH, 28.8 ± 9.38%, P = 0.0073; see Fig. 3C).