Otherwise, a recent study indicated that 3‐hydroxy‐3‐methyl‐glutaryl‐CoA reductase (HMGCR) and acetyl‐coenzyme A cholesterol acetyltransferase 1 (ACAT1) upregulated and ATP‐binding cassette (ABC)A1 downregulated in the lung adenocarcinoma tumor region, which would induce cholesterol dysregulated cellular export.25 Here, HMGCR is linked to neoplasm.