Additionally, the expression of ECSIT was negatively related to YAP program genes but not significantly correlated with known CRC markers such as KRAS and TP53 by correlation analysis with TCGA clinical data (Figure S17A,B, Supporting Information), indicating that ECSIT may have the potential to be used as an independent prognostic biomarker for CRC. Here, KRAS is linked to colorectal carcinoma.