ALDH2 and esophageal squamous cell carcinoma: In patients with esophageal SCC, the population of habitual drinkers with inactive ALDH2 and >100 g of pure ethanol intake per day had a significantly higher risk of developing multiple LVL compared to the population of habitual drinkers with active ALDH2 and <100 g of pure ethanol intake per day (odds ratio [OR] 17.5; 95% CI 1.97–155.59; p = 0.01).21