MEN1 and pituitary gland adenoma: This represented an incidence of multiple pituitary adenomas significantly higher than both that reported previously in a series of unselected sporadic pituitary adenomas (3 out of 116; 2.6%) (15) and that found in a large series of mainly sporadic CD cases (11 out of 658 total, excluding two MEN1 patients; approx. 2%) (16).