Moreover, keratinocyte-derived IL-1β induces IL-17 expression by DETCs (11) and Vγ2+ (in GN, Vγ4 in H-TN) or Vγ4+ (in GN, Vγ6 in H−TN) γδ T cell subsets, including others (collectively referred to as Tγδ17 cells) in the dermis (9), where the latter appear to play a more important role in ACD. This evidence concerns the gene IL1B and ganglioneuroma.