Although some molecules have been previously reported in stroke or CNS bacterial infection, others, such as CXCL-13, TNFRSF4, TNFRSF9, TNFSF14, GZMA, GZMB, GZMH, PDCD1, CXCL-11, CAIX, PTN, and EGF, have never been shown to be associated with the pathogenesis of both diseases. The gene discussed is PTN; the disease is Stroke.