INS and diabetes mellitus: Due to its multifaceted mechanisms of action, encompassing enhancements in insulin sensitivity, promotion of GLUT4 translocation, mitigation of oxidative stress, regulation of carbohydrate metabolizing enzymes, activation of crucial signaling pathways mediated by SIRT1 and AMPK, and potential downregulation of adipogenic genes, resveratrol exhibits considerable promise as a therapeutic agent for the treatment of diabetes and other severe diseases (Bagul and Banerjee, 2015).