PNLIP and Obesity: Consequently, it was determined that the anti-obesity effect of the crude saponins in mice fed a high fat diet including the reduction of blood triacylglycerol may be due to the inhibition of intestinal absorption of dietary fat by platycodin D. In a different study, 10 known triterpenoidal saponins were purified from Platycodi Radix, among them; platycodin A, C, D, and deapioplatycodin D, as all of them showed intestinal absorption inhibition of dietary fats mediated by pancreatic lipase inhibition (Xu et al., 2005).