LPL and obesity due to melanocortin 4 receptor deficiency: It was reported that elderly Caucasian women with MS had lower LPL activity (42); there was a relationship between the rs3779788 variant in LPL and MS in Taiwanese adults (43); LPL variant rs271 was associated with coronary artery disease (CAD) in Europe (44); Malek et al. (45) demonstrated that rs295 in LPL may be indicative for CAD, and rs326 in LPL was associated with the increased risk of obesity in Kuwait.