After surgical resection of the primary tumor, the serum ADM level can be restored to normal.[12, 19] Studies have shown that ADM can promote the proliferation of tumor cells, reduce the apoptosis rate of tumor cells, help tumor cells escape immune surveillance, and promote tumor angiogenesis.[19, 20] There are significant differences in the expression of ADM in malignant and benign ovarian tumor tissues and normal ovarian tissue, suggesting that ADM is mainly produced by the ovarian malignant tumor tissues. This evidence concerns the gene ADM and ovarian benign neoplasm.