Nonetheless, Car6hi cells seem relevant for LG pathology, since autoantibodies for CA-VI are early biomarkers for the diagnosis of Sjogren’s Syndrome [145], and using spatial transcriptomics on mouse LG, we found a rare Car6hi population that was particularly affected by Sjogren’s Syndrome-like disease in NOD.H2b mice [85]. The gene discussed is CA6; the disease is Sjogren syndrome.