CFH and Other metabolic disease: Through its antioxidant and anti-inflammatory properties, RSV could protect against several deleterious environmental factors that initiate AMD [23], such as air pollution; smoking; ultraviolet radiation; metabolic diseases (e.g., diabetes, hypertension, and obesity); dietary fat consumption [24,25,26,27]; and genetic polymorphisms such as cfh and arms2/hrta1 genes [28].