Further, gastric cancer cells secrete extracellular vesicles that alter the expression of various genes in different cells in the tumor niche, for example extracellular vesicles that contain miR-155, miR-193b and miR-210, inducing the expression of chemokines CXCL1 and CXCL8 in fibroblasts [108]. The gene discussed is CXCL1; the disease is gastric cancer.