CXCL1 induces the recruitment of neutrophils into the HCC tumor niche [147]; these cells secrete CCL2 and C-C motif ligand 17 (CCL17, thymus and activation-regulated chemokine (TARC)), which induce the recruitment of monocytes and Treg, respectively [149]. This evidence concerns the gene CXCL1 and hepatocellular carcinoma.