ATXN3 and Machado-Joseph disease: After adjusting for the age at blood collection and the number of CAG repeats in the expanded ATXN3 allele, higher transcript levels of BAX and a lower BCL2/BAX ratio were observed in MJD patients with earlier onset (rho = −0.482, p = 0.003 and rho = 0.393, p = 0.022, respectively) (Supplementary Table S5).