HP and obesity due to melanocortin 4 receptor deficiency: We call special attention to the importance of Protein S100-A8, Heat shock 70 kDa protein 2 and 6, Heat shock 71 kDa protein, and Haptoglobin, which were elevated or exclusively present in US samples, since these proteins were found to be potential biomarkers of the association between obesity and periodontitis during pregnancy in our previous study [14].