Although SVIP silencing resulted in diminished expression of p53 together with increased proliferation rates in p53 wt MCF7 and ZR-75-1 cells but not in p53 mutant T47D and SK-BR-3 cells, the migration of MCF-7 and T47D cell lines was affected by SVIP silencing, suggesting that breast cancer cells with lower SVIP expression might have higher migration ability (Figure 7A–D). This evidence concerns the gene SVIP and breast carcinoma.