When alteration frequency was assessed for different breast carcinoma samples, namely breast invasive carcinoma, breast invasive ductal carcinoma, breast invasive lobular carcinoma, and breast invasive mixed mucinous carcinoma, the frequency of SVIP gene alteration rates varied from 5.88% to 18.18%, where mRNA high alteration was the most common one, with the ratios varying from 5.88% to 11.69% (Figure 2C). The gene discussed is SVIP; the disease is breast carcinoma.