In a prospective observational study carried out by Myhre et al. [214] to investigate the associations of GDF15 in patients hospitalized for COVID-19, it was observed that in patients admitted to the ICU or who died, GDF15 levels up to the 3rd day of hospitalization increased by an average of 1208 pg/mL, while survivors not admitted to the ICU had an average reduction of 86 pg/mL. Here, GDF15 is linked to COVID-19.