TNF and COVID-19: Inflammatory markers and pro-inflammatory cytokines, such as CRP, ferritin, IL-1β, IL-8, TNF-α, and MCP1, show a significant increase in their serum concentrations, and the elevated neutrophil-to-lymphocyte ratio is associated with more severe cases of COVID-19 that can lead to death more easily [31,34,35,36,37].