To further discovery the key biological processes, which these 289 DEGs may involve in, we used R package cluster Profiler v4.0.5 for KEGG enrichment analysis and showed top 30 pathways(q < 0.05): Transcriptional dysregulation in cancer, bladder cancer, chemokine signalling pathway, cellular sense, cell adhesion molecules, ECM−receptor interaction, PI3K − Akt signalling pathway, NF‐kappa B signalling pathway, IL − 17 signalling, Th17 cell differentiation (Figure 5C). The gene discussed is AKT1; the disease is cancer.