CALCA and poikiloderma with neutropenia: Fukushi et al[13] used relevant immunostaining methods to detect the cytokine signatures in 22 cases of PN, and the result revealed that 19 cases had anti-pSTAT6 antibody coloration in the whole epidermal nucleus, 21 cases demonstrated nuclear staining with anti-pSTAT3 antibody, pSTAT1 was expressed in the epidermal nuclei of 8 cases, 6 cases were positive for HLA-DR membrane expression, HABP staining was present in 21 cases, and pSTAT6 and pSTAT3 were expressed in the epidermal KC nucleus of most PN lesions.