In this study samples were divided into groups based allergen sensitization status (allergic, non-allergic asthma), vitamin D content (deficiency < 20 ng/ml, insufficiency 20–30 ng/ml, normal amount 30–50 ng/ml) and assessed the type of VDR gene polymorphisms (rs7975232, rs1544410, rs731236, rs3847987, rs2228570, rs11168293) and VDBP gene polymorphisms (rs7041, rs4588) in asthma subjects and control group. This evidence concerns the gene GC and allergic asthma.