The molecular mechanism underlying this pathological process resembles that of LNMAT2. In the nucleus of bladder cancer cells, ELNAT1 forms a DNA-RNA triplex with the promoter of small ubiquitin-like modifier (SUMO)-conjugating enzyme 9 (UBC9) and, in association with the RNA‐binding protein HNRNPA1, activates the transcription of the UBC9 gene. The gene discussed is UBE2I; the disease is urinary bladder carcinoma.