VEGFC and neoplasm: Since FGF-1, VEGF-C and VEGF-A are all known inducers of lymphangiogenesis [89, 141, 147], the results of Godet et al. shed light on a possible mechanism by which NEAT1 may activate FGF, VEGF-C or VEGF-A signaling in cancer, thereby promoting tumor lymphangiogenesis and lymphatic metastasis.