MPPE1 and neoplasm: These effects were attributed to FLCN deletion selectively in cDC1s, as evidenced by increased MC38 tumour growth in Batf3–/–:FlcnΔDC mixed chimeras or Xcr1cre/+Flcnfl/fl mice with cDC1-specific FLCN deletion (Fig. 3h and Extended Data Fig. 7m).