ADA and tuberculosis: ROC analysis demonstrated that the AUC for the developed multi-parameter prediction model, as well as for the individual application of T-SPOT.TB, ADA, lymphocyte/neutrophil ratio, and the combined use of ADA and lymphocyte/neutrophil ratio in diagnosing TPE, were as follows: 0.845 (95% CI 0.800–0.891), 0.710 (0.649–0.772), 0.771 (0.712–0.830), 0.691 (0.629–0.753), and 0.726 (0.667–0.784), respectively.