CRP and Pleural effusion: The analysis revealed that age, blood culture, laboratory findings including C-reactive protein, procalcitonin, alanine aminotransferase (ALT), aspartate aminotransferase (AST), albumin, total bilirubin, blood urea nitrogen (BUN), creatinine, lymphocyte, neutrophil-to-lymphocyte ratio (NLR), platelet, prothrombin time, and d-dimer, as well as radiological findings such as septations within the abscess, rim enhancement, internal gas bubble, and pleural effusion were significantly associated with sepsis in the derivation cohort.