Previously, we showed that ELF-EMF has the potential to trigger apoptosis/necroptosis in different breast cancer cells27,28; here, by selecting two different GBM cell lines with different P53 statuses (U87 and U251), at the first step, we tried to investigate the dependency of ELF-EMF anti-cancer effect on this gene. This evidence concerns the gene TP53 and glioblastoma.