METTL3 and Insulin resistance: In addition, Igf2bp2 is identified as a Type 2 diabetes‐associated gene and downregulations of Igf2bp2 mRNA level both in visceral or subcutaneous adipose were correlated with insulin resistance in diabetic patients,[52] suggesting both Mettl3 and Igf2bp2 may regulate glycolysis in mature white adipocytes and preadipocyte proliferation for glycemic control.