Furthermore, in B cell chronic lymphocytic leukemia (B-CLL), lower IgM expression, when compared with healthy controls, resulted from defects in glycosylation of μHC and CD79a, leading to their retention in the endoplasmic reticulum (ER), possibly leading to the lower IgM expression [73]. The gene discussed is CD79A; the disease is B-cell chronic lymphocytic leukemia.