The results showed that a non-mature stromal type and a low stromal volume were significantly positively associated with TAIs infiltrating within the stroma in PDAC (both p < 0.0001) (Fig. 2d, e), particularly with an increase in CD68+ macrophage infiltration in the whole tumor (p = 0.0321 for stromal maturity [(Fig. 2f) and p = 0.076 for stromal volume (Fig. 2g)]. This evidence concerns the gene CD68 and neoplasm.