STING1 and periodontitis: In a study by Elmanfi et al. (2021), immunohistochemical analyses indicated that in periodontitis, strong STING accumulation was detected in the basal epithelium and around vessel walls in the connective tissue; however, STING was weakly present in healthy gingiva, similar to what we observed in our P. gingivalis in vitro HGF infection model.