Given BBB circadian disruptions occur following stress responses and in several neurological disorders, including brain metastasis, epilepsy, AD, and PD (Schurhoff and Toborek, 2023), future studies determining the relationship between FABP7 signaling, brain injury, BBB permeability, stress, and sleep/circadian rhythms will be important for the treatment of neurological disorders and diseases. Here, FABP7 is linked to Parkinson disease.