CAV1 and atrial fibrillation: Other interesting loci associated with AF in this cohort include rs6666258, an intron variant in KCNN3, which encodes a potassium channel protein which is important for atrial repolarization and has previously been associated with AF in other patient populations (40), as well as the very common rs11773845, an intron variant in CAV1 encoding caveolin-1 which has a great variety of functions and has also been associated with AF in other patient populations (41).