Fam et al. reported that the CYP24A1 rs2762939 G/G genotype was significantly associated with stroke-like vascular acute events, also known as acute coronary syndrome, while the genotypes of CYP24A1 rs4809960 and CYP27B1 rs703842 were not associated with the incidence of acute coronary syndrome (41). This evidence concerns the gene CYP27B1 and acute coronary syndrome.