Patients and families should be aware that achondroplasia is transmitted in an autosomal dominant manner and is caused by genetic alterations (pathogenic missense variants in FGFR3) occurring de novo in 80% of individuals with achondroplasia, while 10%–20% of the cases inherited the mutation with 100% penetrance from an affected parent (7). This evidence concerns the gene FGFR3 and achondroplasia.