Here, the DEGs of mesophyll cells in TN1 and YHY15 varieties were mainly related to “phenylalanine, tyrosine, and tryptophan biosynthesis,” “MAPK signaling pathway,” and “phenylalanine metabolism.” PALs is a crucial enzyme that mediates the resistance to BPH by regulating the biosynthesis and accumulation of SA and lignin (He et al., 2020). Here, CTSC is linked to benign prostatic hyperplasia.