Encouraging result was observed for the diagnostic accuracy of CSF-ADA to diagnose TBM in adults with summary estimates of sensitivity as 0.85 (95% CI: 0.77-0.90), specificity as 0.90 (95% CI: 0.85-0.93) and diagnostic odds ratio of 48 (95% CI: 26-86) (Figure 4). Here, ADA is linked to meningeal tuberculosis.