TLR2 and irritable bowel syndrome: The genetic analysis of TLR2 showed that among the SNPs TLR2 gene Arg753Gln (rs5743708), the AA genotype of polymorphism was found significantly less frequently in group 2 [49 (76.6%) patients] and in IBS [96 (78.1%) patients] (P < .02), compared to the control group.