TLR4 and irritable bowel syndrome: The genetic analysis of TLR4 showed that CC and CG genotype-819T/C (rs1800871) TLR4 gene polymorphisms were detected in all study groups; GG genotype-819T/C (rs1800871) polymorphism of the TLR4 gene was not detected in patients with ADPC concomitant with IBS; no significant difference was found among the study groups.