TLR4 and irritable bowel syndrome: The general model of heredity validated the relationship of frequency of SNP genotypes of IL10-592C/A (rs1800872), TLR4 Thr399ile (rs4986791), and TLR2 Arg753Gln (rs5743708) genes with the tendency to emergence of IBS that is in concordance with the data of the multiplicative model of heredity.