We also found that generally younger age, male gender, being overweight/obese, central adiposity, TG ≥6.9 mmol/L, non‐HDL‐C ≥3.37 mmol/L, lipid‐lowering medications, and pre‐diabetes/T2DM were associated with abnormal ALT using different definitions. The gene discussed is GPT; the disease is diabetes mellitus.