To further confirm the role of Runx2 in liver fibrosis, Runx2 overexpression mice were generated by injecting HBAAV‐Runx2 (1 × 1012 V g/mL, portal vein) for 3 weeks, and then the mice were subjected to olive or CCl4 for 4 weeks (Figure 4A). Here, RUNX2 is linked to Hepatic fibrosis.