RUNX2 and metabolic dysfunction-associated steatotic liver disease: We occasionally observed that the transcriptional protein, runt‐related transcription factor 2 (Runx2), was significantly increased during the progression of non‐alcoholic fatty liver (NAFLD) and predominantly expressed in activated HSC in the liver,8 which raises a question of whether Runx2 plays a critical role in the regulation of HSC activation.