SBP: systolic blood pressure; DBP: diastolic blood pressure; CCU: cardiac care unit; AF: atrial fibrillation; CHF: congestive heart failure; CKD: chronic kidney disease; non-STEMI: non-ST segment elevation myocardial infarction; DM: diabetes mellitus; HB: hemoglobin; CR: creatinine; PT: prothrombin time; ACEI/ARB: angiotensin-converting enzyme inhibitors/angiotensin receptor blockers; SOFA score: sequential organ failure assessment score; CCI: charlson comorbidity index; ICU LOS: intensive care unit length of stay. The gene discussed is ACE; the disease is chronic kidney disease.