Hs-CRP: high sensitivity C-reactive Protein, CHD: coronary heart disease, CVD: cardiovascular disease, HDL-C: high-density lipoprotein cholesterol, LDL-C: low-density lipoprotein cholesterol, BMI: body mass index, ApoAI: apolipoprotein AI, ApoB: apolipoprotein B HR: hazard ratio, CI: confidence intervals, RERI: relative excessive risk interaction, AP: attributable proportion. The gene discussed is APOB; the disease is cardiovascular disorder.