The associations of HDL-C < 40 mg/dL, ApoAI < 1.60 g/L, and ApoB < 0.7 g/L with CHD were heterogeneous between the subgroups of normal and increased hs-CRP with I2 > 67% and P < 0.1 The relationship of LDL-C ≥ 160 mg/dL with CVD was heterogeneous between subgroups of normal and increased hs-CRP (I2 = 84.3%, P = 0.011), while the associations of non-HDL-C ≥ 190 mg/dL, and ApoB < 0.7 g/L with CVD showed heterogeneity with I2 of 72.6%, and 72.9% and P < 0.1 (Fig. 1). Here, APOB is linked to coronary artery disorder.