TRPV4 channels are involved in the recruitment of neutrophils and macrophages during lung injury.378 In addition, TRPV4 has been associated with pulmonary edema and pulmonary fibrosis.379 Therefore, TRPV4 is a novel target for COVID-19 treatment.380 TRPs are involved in pathophysiological processes that largely overlap with the symptoms of COVID-19. This evidence concerns the gene TRPV4 and pulmonary edema.