Many survivors of severe COVID-19 display signs of lung fibrosis even month(s) after infection and clinical data identified activation of EGFR as a key regulator inducing fibrosis in lung tissue after SARS-CoV-2 infection (Vagapova et al, 2021), further supporting a critical role of EGFR in COVID-19 and post-acute COVID-19 syndrome (PACS). This evidence concerns the gene EGFR and COVID-19.